How to automate an Obsidian second brain with AI agents

7 real setups for an Obsidian second brain, most-discussed first. Steps come from each source; the full prompt is one click away.

Quick answer

7 real setups on agentsetups show how people automate an Obsidian second brain with AI agents. Agents used: Claude (5), Grok Bot (1), OpenCode (1), Hermes Agent (1).

Fastest start (from Use Obsidian folders as Claude Code’s shared memory by v. Splicer):

  1. Create /00-inbox, /01-projects (each with its own CLAUDE.md), /02-memory and /03-docs.
  2. Keep people, decisions and bugs in the memory tree.
  3. Put stack and rules in each project’s CLAUDE.md.

Tools named most: Obsidian (6).

Last updated · based on 336 use cases on agentsetups, each credited to its author.

1. Use Obsidian folders as Claude Code’s shared memory

Inbox, projects (each with CLAUDE.md), a memory tree for people/decisions/bugs, and docs Claude reads.

  1. Create /00-inbox, /01-projects (each with its own CLAUDE.md), /02-memory and /03-docs.
  2. Keep people, decisions and bugs in the memory tree.
  3. Put stack and rules in each project’s CLAUDE.md.

Claude · tools: Obsidian · by v. Splicer (DEV post, 8 Oct 2026) · source

2. Give your trading bot an Obsidian second brain

Grok Bot and Claude Code built a 28,728-file vault from scattered charts, screenshots and notes; it then refused a trade.

  1. Gather charts, screenshots and notes from their separate places.
  2. Have the agents build an Obsidian vault from them.
  3. Have the trading bot check the vault before acting.

Claude, Grok Bot · tools: Obsidian · by Spike 1% (X post, 4 Sep 2026) · source

3. Run networking through Boardy, Claude Code and Obsidian

Boardy finds a fit and emails you; Claude Code reads it with Obsidian context; notes loop back to Obsidian.

  1. Boardy finds the fit and emails you.
  2. Claude Code reads it in Gmail with your context from Obsidian.
  3. You decide; Boardy takes the meeting and writes notes.
  4. Everything loops back into Obsidian.

Claude · tools: Boardy, Gmail, Obsidian · by EZ (X post, 9 Sep 2026) · source

4. Distil every coding session into searchable notes

Drop a raw Claude session in, distil it into a tagged note, then search by meaning: make search q="…".

  1. After each session, feed the raw Claude transcript to a distiller that writes a tagged note.
  2. Index notes for semantic search.
  3. Query later, e.g. make search q="how did I do an aptos coin transfer?".

Claude · by Rajdeep Singha (X post, 12 Sep 2026) · source

5. Ramble into a daily note, let OpenCode make sense of it

Dictate unfiltered thoughts into an Obsidian daily note all day; each evening OpenCode extracts tasks, summarises and sets goals.

  1. Through the day, dictate whatever you are doing or thinking into your Obsidian daily note.
  2. At the end of each day, have OpenCode read the daily note from the vault.
  3. Have it extract tasks, summarise your thoughts and set goals for tomorrow.
  4. Over weeks, use the notes to build a personal charter or a tag-based heatmap of your time.

OpenCode · tools: Obsidian · by /u/Billy-Fong-2007 (Reddit, 14 Oct 2026) · source

6. Build an Obsidian knowledge base in Claude Cowork

A custom MCP server + skills for Obsidian in Claude Cowork became the most valuable system; teammates report efficiency gains.

  1. Build a custom MCP server for your Obsidian vault.
  2. Add skills for how Cowork should read and write notes.
  3. Onboard teammates to the same knowledge base.

Claude · tools: Obsidian, MCP · by FiL Dev (X post, 15 Sep 2026) · source

7. Run an AI OS on Hermes with an Obsidian graph

Hermes runs 24/7 across 8 domains via Telegram; a desktop AI builds; every rule and SOP is saved as a note in Obsidian.

  1. Desktop AI handles heavy coding and builds the systems.
  2. Hermes runs 24/7 on a server; chat, monitor and build tools from Telegram.
  3. Use Obsidian as the shared knowledge graph: every rule, asset and SOP is a human-readable note.
  4. When agents solve an issue or learn a rule, they commit it to the graph.

Hermes Agent · tools: Obsidian, Telegram · by MGDigital (X post, 13 Sep 2026) · source

Questions people ask

Which AI agent is best for automating an Obsidian second brain?

In the 7 setups here, the agents named are Claude (5), Grok Bot (1), OpenCode (1), Hermes Agent (1). That is what people used, not a quality ranking.

What do I need to automate an Obsidian second brain with an AI agent?

An agent (Claude, Grok Bot, OpenCode are the most common here) and, in these sources, tools such as Obsidian. Each setup lists only the tools its source states.

Is there a prompt I can copy?

Yes. Every use-case page has a copyable prompt with the steps embedded and a “Based on” credit line, for example Use Obsidian folders as Claude Code’s shared memory.

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